Showing posts with label medicine. Show all posts
Showing posts with label medicine. Show all posts

Malcolm Gladwell on drug research

From Malcolm Gladwell's article, "Why is it so difficult to develop drugs for cancer?":
An early financial backer of Chen's was Michael Milken, the junk-bond king of the nineteen-eighties who, after being treated for prostate cancer, became a major cancer philanthropist. "I told Milken my story," Chen said, "and very quickly he said, 'I'm going to give you four million dollars. Do whatever you want.' Right away, Milken thought of Russia. Someone had told him that the Russians had had, for a long time, thousands of chemists in one city making compounds, and none of those compounds had been disclosed." Chen's first purchase was a batch of twenty-two thousand chemicals, gathered from all over Russia and Ukraine. They cost about ten dollars each, and came in tiny glass vials. With his money from Milken, Chen then bought a six-hundred-thousand-dollar state-of-the-art drug-screening machine. It was a big, automated Rube Goldberg contraption that could test ninety-six compounds at a time and do a hundred batches a day. A robotic arm would deposit a few drops of each chemical onto a plate, followed by a clump of cancer cells and a touch of blue dye. The mixture was left to sit for a week, and then reexamined. If the cells were still alive, they would show as blue. If the chemical killed the cancer cells, the fluid would be clear.
Read on.

*Buy books by Malcolm Gladwell at Amazon.

Bomb Squad poster (link roundup)



Bomb Squad poster via these sites.

And a few more links:

1. The writer of niche blog Joe Mathlete Explains Today's Marmaduke really wishes United Features Syndicate would send him a cease and desist letter to give him an excuse to stop blogging. Via.

2. 10 years later and we've seen no meaningful developments from genetics research.

3. Tiny Red Riding Hood and the Very Big Bad Wolf.

*Previously: If Marmaduke was a horror movie.

*Buy home DNA kits at Amazon.

Little Red Riding Hood by Tara Jacoby (link roundup)




Little Red Riding Hood and Mother Nature by Tara Jacoby.

And a few more links:

1. Mushroom Kingdom painting.

2. Interesting article about developments in battlefield medicine. There's lots of cutting edge stuff. But sometimes, it's the old tricks that work the best:
One of the most important innovations is a reemphasis on one of the oldest medical implements on the battlefield: the tourniquet. It was frowned upon in previous years because doctors feared it could cause long-term limb damage. Servicemen are now issued a Combat Action Tourniquet, dubbed CAT, made by Composite Resources, of Rock Hill, S.C.

Two CATs are now issued to every soldier. They are easy to use because each tourniquet has a black plastic lever that tightens it. Marines often go on foot patrols with tourniquets loosely strapped high on their thighs, so they can begin cranking right away if a foot is blown off.
Via these sites.

3. Swordswoman and rock monsters.

*Previously: Tough Red Riding Hood.

*Buy military patches at eBay.

Plague Doctor (link roundup)



Plague doctor from the National Museum of Health and Medicine at the Walter Reid Medical Center. See more disturbing exhibits in this photo set, including the Wall of Facial Injury.

And a few more links:

1. Anatomical cross-section of a Cootie (from the game Cootie).

2. Penny Arcade's comic about the birds and the bees, and a remix.

3. For my favorite reader, new Massachusetts Senator Scott Brown's nigh-naked Cosmo centerfold. Relatedly, Jon Stewart mocks Coakley's campaign.

*Previously: You've got crabs Charlie Brown.

*Buy vintage medical equipment at eBay.

New Moon paper toys (link roundup)



Bella, Edward (just add glitter), and shirtless Jacob paper toys can be downloaded here. Via.

And a few more links:

1. How to move photos and video from Flickr to Picasa. Via.

2. The History Channel is looking for marksmen for a new show: "Looking for anyone with mind-blowing shooting skills and a big personality to take on exciting physical challenges with multiple guns and mystery projectile weapons."

3. Israel is moving to a system to reward and encourage organ donors - - agree to donate your organs and you move up the list to become a recipient.

*Previously: Puppet New Moon.

*Buy Twilight toys at eBay.

Found item sheep (link roundup)



(New to me, but not to the web) Sheep made out of telephones by Jean-Luc Cornec at the Museum of Telecommunication in Frankfurt. Via these sites.

And a few more links:

1. The Gorilla Tough Cuff is the first blood pressure cuff tough enough for a 300-pound gorilla.

2. Todd McFarlane received over 350 rejection letters before his first professional job.

3. Clearly I've made it as a blogger - - just got offered a media pass to Trump's Miss California pageant. I'm assured that "anything can happen" at the event.

*Previously: Found item robots.

*Buy McFarlane toys at eBay.

Lego mask (link roundup)




Lego mask by Cole Blaq.

And a few more links:

1. Sherlock Holmes ARG. Via.

2. Jason Voorhees cupcakes.

3. Company charged with marketing a bone growth product that migrated through patients' bodies and grew bone where bone shouldn't be. Via.

*Previously: Bone mask.

*Buy Sherlock Holmes toys at eBay.

Burning Man patches (link roundup)



One of several Burning Man patches on display here.

And a few more links:

1. Geeks face off on the poster for King Con Brooklyn. Via.

2. Pro-health care reform poster.

3. Mount Fuji looks like a flying mountain in this photo. Via.

*Previously: Bizarre NASA patches.

*Buy patches at eBay.

Linus regrets seeing The Great Pumpkin (link roundup)



Monstrous Great Pumpkin by J. Bone. See it in high-res, as well as Charlie Brown caling Lucy a bitch, here. Via.

And a few more links:

1. Massive layoffs at Forbes.

2. Go here to find out how people make it to the major leagues as umpires and what they get paid.

3. I'd like to make my small contribution to the cause of making it legal to pay for bone marrow donations. Via.

*Previously: Lego Pumpkin Monster.

*Buy Peanuts toys at eBay.

Funny disclaimer at Ambien website (link roundup)



Yes, that's right an Ambien pill is not actually big enough for four people to stand on. Via these sites.

And a few more links:

1. In response to the Darth Vader with harmonica image I posted earlier today, Adam points out that there's a video, too.

2. Nancy Dorsner's robot is currently being featured at the Museum of Science in Boston, which reminds me that this Saturday is free museum day. My family is going to check out the found item animal sculptures at the Noah's Ark exhibit at the Skirball Cultural Center.

3. Alice in Wonderland illustration.

*Previously: Warning, your uterus may be a choking hazard.

*Buy Alice in Wonderland toys at eBay.

Canvas bag doubles as a luchador mask (link roundup)



This reusable canvas bag can double as a luchador mask if you need to wrestle without warning. Via.

And a few more links:

1. The Duracell Instant Power Charger for USB Compatible Devices which received a rave review from Gizmodo is one of Amazon's deals of the day.

2. Tomopop is giving away a toy.

3. UC Irvine in California settled several lawsuits that arose after it was discovered that doctors at the school's Center for Reproductive Health stole eggs for years and gave them to other women. Two of the doctors fled the country.

*Previously: Papercraft fertility idol.

*Buy fertility idols at eBay.

Bayonetta Cosplay (link roundup)



Bayonetta cosplay spotted here. Here's another shot.

And a few more links:

1. Why are placebos becoming more effective? Via.

2. Jason Kottke says he just spent a bunch of money on a new MacBook and iPhone and is having trouble convincing himself that the money was worth it. By comparison, all of my computer purchases have been PCs, purchased when I felt I absolutely had to have a new one. I've always felt that the new computer was so advanced as to be from a different species.

3. Relatedly, I have a brand new laptop. Can anyone suggest a good laptop bag that I can travel with?

*Previously: Yuki 7 cosplay.

*Buy cosplay books at Amazon.

Han Solo Adventures (link roundup)




Stacy Davidson is roughly 25% done on her SCUMM engine-style game Han Solo Adventures. Via these sites.

And a few more links:

1. Interesting logo for first aid at a train station in the Czech Republic.

2. The Alien uses the bathroom. Via.

3. And Aliens sketch cards by Otis Frampton.

*Previously: Ominous first aid tips.

*Buy Giger art collections at Amazon.

Lego flying car (link roundup)



Lego flying car by Jordan Schwartz.

And a few world news links courtesy of Thomas Barnett:

1. For the first time, China enforced sanctions against North Korea, confiscating vanadium, which can be used in missile casings.

2. Henry Kissinger praises Obama's performance to date.

3. A new way to explain to patients what a medical procedure will entail - - create a hospital room in Second Life.

*Previously: Rocket car.

*Buy pulp magazines at eBay.

Baboons take apart some luggage (link roundup)






Apparently real, video of a bunch of baboons in Knowsley Safari Park taking apart the luggage on top of a car. See also: Monkey steals food.

And a few more links:

1. Western dragons, Eastern dragons, and everything in between.

2. Americans spent $34 billion on alternative medicine in 2007. In other news, look for Struan's Herbal Multivitamin in a store near you soon.

3. Escher pattern in the real world.

*Previously: Armored mandrill.

*Buy mandrills at eBay.

The Dead Weather concert poster (link roundup)



The Dead Weather concert poster on sale for $40 here.

And a few more links:

1. A dog owner couldn't stop her dog from biting, and even Cesar Milan's help proved ephemeral, so she turned to a veterinary dentist who specializes in canine disarming:
Instead of extracting the four canines, Nielsen cuts away 4 millimeters of tooth using a CO2 laser. He acid-etches the live pulp within, fashions a bell-shaped cavity that he packs with two kinds of human-grade composite, and light-cures the top for a smooth, flat finish. He also blunts the extra set of pointy incisors.
Want to know how much it costs?

2. Doctor questions "Why bogus treatments and crackpot medical theories dominate" the Huffington Post.

3. Sad: Erin Andrew was hiding out at her mom's place and had to call 911 because paparazzi had managed to get into the gated community. Meanwhile, ESPN nobly banned all NY Post writers from appearing on ESPN tv and radio due to anger over the Post running naked photos of Andrews. Well, nobly banned them for nine days before rescinding the ban.

*Previously: "Child Molester" pops onto screen during weather forecast.

*Buy concert posters at eBay.

Robot paper toy (link roundup)



Papercraft robot with rotating head. Download it here (the top of the page scrolls horizontally). And if you're in the mood for papercraft, here's a bunch of boxing foxes.

And a few more links:

1. Parody of Shell's logo emphasizes its recent poor earnings.

2. Mayo Clinic doctors say experiments show no relation between food choice and autism. But hey, who are you going to believe? Science or Jenny McCarthy?

3. Hasbro's Star Wars 2009 Figure Poster, downloadable as a pdf.

*Previously: Jenny McCarthy as Rosie the Riveter.

*Buy Star Wars Lego minifigs at eBay.

OC Weekly cover by Jim Rugg (link roundup)



Cover story by Jim Rugg for the OC Weekly. The tease for the featured article says, "Cancer wasn’t killing Jack Jessee fast enough. Did that drive his wife to hire a hit man?"

And a few more links:

1. The new issue of XBox Magazine features Bioshock 2. Cover scan here, and more scans will be uploaded.

2. An isotope called technetium-99m, is used in more than 40,000 medical procedures every day in the US to test for cardiac disease, cancer and kidney trouble. It mostly comes from a 51-year-old reactor in Ontario, which has been shut down due to safety problems. Here's a semi-alarmist article about the problems that shortage might cause.

3. Since the original winner of the Steam Crow giveaway never responded, I was forced to choose a new winner. "marshman" was randomly chosen and hopefully has received an email from me.

*Previously: LA Weekly cover by Jim Rugg.

*Buy Bioshock toys at eBay.

Boxing werewolf (link roundup)



Fire-breathing, boxing werewolf by Dave Crosland. Spotted at the latest Gallery 1998 show, "Beasts from the Bay."

And a few more links:

1. Memo advising Conde Naste employees that they have to clean up their own dishes and stop expecting the interns to do it.

2. Soldiers use pigs to practice battlefield medical treatment.

3. Another sign that history will be kind to George Bush - - Time examines his refusal to pardon Scooter Libby despite tremendous pressure from Dick Cheney.

*Previously: Crispin Porter + Bogusky intern auction.

*Buy boxing posters at eBay.

Found item robots (link roundup)




Two of the found item robots on sale in the reclaim2fame Etsy shop. Via.

And a few more links:

1. Don't look down this rabbit hole for too long. Via.

2. Video of matador Israel Lancho getting gored. Not for the squeamish.

3. Josh Silver created super cheap glasses where the lenses are filled with fluid that you can adjust yourself with a syringe. No doctor or fancy equipment needed. Won't help people with astigmatisms, though. You can contribute here. Via.

4. Porn stars, actors, and actresses that are really smart.

*Previously: The matador of shame.

*Buy bullfight posters at eBay.